New symmetrical quinazoline derivatives selectively induce apoptosis in human cancer cells
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New symmetrical quinazoline derivatives selectively induce apoptosis in human cancer cells.
In the search of new symmetrical derivatives with anticancer activity, we have looked for novel compounds able to induce a selective proapoptotic mechanism in cancer cells. The potential antitumoral activity of several quinazoline derivatives was evaluated in vitro examining their cytotoxic effects against human breast, colon and bladder cancer cell lines. The IC(50) value of the compounds that...
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ژورنال
عنوان ژورنال: Cancer Biology & Therapy
سال: 2006
ISSN: 1538-4047,1555-8576
DOI: 10.4161/cbt.5.7.2841